Mexican Italian trattoria Piacere Mio

Most Upper East Side restaurants pick one cuisine and stick to it. Piacere Mio breaks that rule by blending Mexican and Italian flavors under one roof. The concept might sound unusual, but the menu leans into familiar comforts—think handmade pastas with a spicy kick or wood-fired pizzas topped with chorizo and Oaxaca cheese. It’s an approach that works for anyone craving something beyond the usual neighborhood options.

The place sits at 173 E 99th St, a stretch of the avenue where bodegas and brownstones give way to small eateries with loyal followings. Unlike the polished bistros a few blocks south, this corner feels lived-in, with the kind of energy that comes from regulars stopping by after work. The kitchen keeps things simple: wood-fired dishes, fresh masa for tortillas, and a short but thoughtful wine list that doesn’t overcomplicate the experience. No need to choose between two cuisines when you can have both.

They don’t take reservations, so showing up early or late can save you a wait. If you’re curious about the menu or want to check availability, a quick call to (646) 454-1246 will sort out the details. For directions, the map here—https://www.google.com/maps/place?ftid=0x89c259d81c460ae3:0x46a8b965974b6982—should get you there without fuss. It’s the kind of spot that doesn’t need a grand entrance, just good food and a little patience.