Ernest G Depuey, MD

Midtown West sees its share of internists, but Ernest G Depuey, MD has quietly become a familiar name along the hospital corridor. The practice sits at 1000 10th Ave, New York, NY 10019, where the avenue’s steady hum blends with the neighborhood’s medical rhythm. Internists here tend to focus on the long game—chronic conditions, preventive care, and the slow unraveling of symptoms that don’t fit neatly into a single specialty.

Patients often arrive after a referral or a search for someone who can connect the dots between bloodwork, imaging, and the occasional mystery ache. The office handles routine physicals, hypertension management, diabetes care, and minor procedures like joint injections or skin biopsies. There’s also a practical side to the work: pre-op evaluations, travel medicine, and the kind of follow-up that keeps small issues from becoming larger ones. (212) 523-7171 is the number to call when the usual quick fixes haven’t worked.

Finding a doctor in New York can feel like navigating a maze of insurance networks and appointment slots. This part of 10th Avenue doesn’t offer the flash of tourist-heavy blocks, but it’s where locals end up when they need more than a walk-in clinic can provide. The area’s mix of residential high-rises and hospital-adjacent buildings means the waiting room might hold a retiree from Hell’s Kitchen or a nurse grabbing a same-day visit between shifts.

For directions, the map at this link will drop a pin at the entrance. The building’s glass doors open to a lobby that, like most in the neighborhood, doesn’t linger in memory—but the care often does.