Despina Siolas, M.D., PhD

Cancer specialists on the Upper East Side rarely occupy the same conversation as the neighborhood’s brownstones and delis, yet they’re part of its daily rhythm. Despina Siolas, M.D., PhD sees patients at 1305 York Ave 12th Floor, a building that blends into the blocks between the East River and Central Park. Oncology consultations here follow the same quiet efficiency as the rest of York Avenue—no fanfare, just the essentials. A restroom is available on-site, a small but practical detail for anyone spending hours in appointments. They can be reached at (646) 962-6200 to schedule visits or ask questions.

Upper East Side medical offices often share elevators with research labs and private practices, and this one is no exception. The address places it within walking distance of Weill Cornell Medicine, a connection that shapes the kind of care offered—specialized, evidence-based, and tied to academic standards. Directions can be found here. If you’re heading there, bring a book; the wait, like the neighborhood itself, moves at its own steady pace.