Businesses in Downtown Manhattan

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Apicha Community Health Center

Apicha Community Health Center

Downtown Manhattan

3.0 (152 reviews)

400 Broadway New York, NY 10013 United States

Housing Works - Keith D. Cylar Community Health Center

Housing Works - Keith D. Cylar Community Health Center

Downtown Manhattan

4.3 (144 reviews)

743-749 E 9th St New York, NY 10009 United States

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Betances Health Center

Betances Health Center

Downtown Manhattan

3.7 (89 reviews)

280 Henry St New York, NY 10002 United States

Community Healthcare Network – Lower East Side / Catherine M. Abate

Community Healthcare Network – Lower East Side / Catherine M. Abate

Downtown Manhattan

2.7 (60 reviews)

255 E Houston St New York, NY 10002 United States

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Ryan-Nena Community Health Center: Cruz Roxana MD

Ryan-Nena Community Health Center: Cruz Roxana MD

Downtown Manhattan

3.6 (7 reviews)

279 E 3rd St, New York, NY 10009

Metro Community Health Centers – Downtown Brooklyn

Metro Community Health Centers – Downtown Brooklyn

Downtown Manhattan

3.2 (5 reviews)

177 Livingston St UNIT Ll Brooklyn, NY 11201 United States

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Murayama-Green Robert MD

Murayama-Green Robert MD

Downtown Manhattan

5.0 (2 reviews)

400 Broadway New York, NY 10013 United States

Downtown Brooklyn Health Center

Downtown Brooklyn Health Center

Downtown Manhattan

4.5 (2 reviews)

57 Willoughby St Brooklyn, NY 11201 United States

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PS 64

PS 64

Downtown Manhattan

5.0 (1 reviews)

600 E 6th St New York, NY 10009 United States

ScanVan, mobile van

ScanVan, mobile van

Downtown Manhattan

0.0 (0 reviews)

200 Varick St New York, NY 10014 United States

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NYC Community Health Center

NYC Community Health Center

Downtown Manhattan

0.0 (0 reviews)

73-21 37th Rd Jackson Heights, NY 11372 United States

Vision Urbana Health & Wellness Center

Vision Urbana Health & Wellness Center

Downtown Manhattan

0.0 (0 reviews)

60 Madison St New York, NY 10038 United States

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About Downtown Manhattan

Downtown Manhattan is the heart of the city's business and financial district. Home to Wall Street, the New York Stock Exchange, and the Federal Reserve Bank, it's where America's economic power is concentrated. But there's more to Downtown than just finance - it features historic sites like the 9/11 Memorial & Museum, cultural attractions such as the South Street Seaport, and architectural marvels like One World Trade Center.

The area has transformed in recent decades, evolving from a primarily business-focused neighborhood to a vibrant mixed-use district. With waterfront access, cobblestone streets in areas like Stone Street, and proximity to Brooklyn via the iconic Brooklyn Bridge, Downtown Manhattan offers visitors a blend of American history, modern architecture, and diverse dining options.

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Manhattan Businesses helps visitors discover local restaurants, shops, services, attractions, nightlife, wellness providers, professional services, and useful places across every major Manhattan neighborhood.

Browse organized business profiles with categories, locations, ratings, reviews, photos, maps, phone numbers, websites, and practical contact details in one simple Manhattan guide.

Whether you live in New York City or are planning a visit, Manhattan-NYC.com makes it easier to compare local places, explore nearby options, and find trusted businesses by neighborhood and interest.