Businesses in Downtown Manhattan

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Well Nest, Inc.

Well Nest, Inc.

Downtown Manhattan

0.0 (92 reviews)

315 E 10th St, New York, NY 10009

LESC - Su Casa

LESC - Su Casa

Downtown Manhattan

3.7 (80 reviews)

7 Gouverneur Slip E New York, NY 10002

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Lafayette Medical Approach

Lafayette Medical Approach

Downtown Manhattan

4.6 (55 reviews)

233 Lafayette St New York, NY 10012

MGA Crisis Intervention

MGA Crisis Intervention

Downtown Manhattan

0.0 (31 reviews)

100 Church St New York, NY 10007

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Hazelden Betty Ford Foundation

Hazelden Betty Ford Foundation

Downtown Manhattan

3.7 (26 reviews)

283 W Broadway New York, NY 10013

Realization Center

Realization Center

Downtown Manhattan

4.4 (15 reviews)

25 E 15th St New York, NY 10003

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Beth Israel Methadone Clinic

Beth Israel Methadone Clinic

Downtown Manhattan

3.6 (11 reviews)

26 Avenue A New York, NY 10009 United States

Mount Sinai Beth Israel, Chemical Dependency

Mount Sinai Beth Israel, Chemical Dependency

Downtown Manhattan

3.4 (11 reviews)

9 Nathan D Perlman Pl, New York, NY 10003

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The Recovery Book

The Recovery Book

Downtown Manhattan

2.6 (10 reviews)

225 Varick St New York, NY 10014

The Weare Foundation

The Weare Foundation

Downtown Manhattan

0.0 (8 reviews)

52 Walker St #124 New York, NY 10013

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INSTASHIFT Corp

INSTASHIFT Corp

Downtown Manhattan

5.0 (7 reviews)

477 Broadway 2nf fl #1291 New York, NY 10013

LESC - Pencer House

LESC - Pencer House

Downtown Manhattan

3.3 (7 reviews)

630 E 6th St New York, NY 10009

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Odyssey House Inc.

Odyssey House Inc.

Downtown Manhattan

1.8 (5 reviews)

120 Wall St New York, NY 10005

About Downtown Manhattan

Downtown Manhattan is the heart of the city's business and financial district. Home to Wall Street, the New York Stock Exchange, and the Federal Reserve Bank, it's where America's economic power is concentrated. But there's more to Downtown than just finance - it features historic sites like the 9/11 Memorial & Museum, cultural attractions such as the South Street Seaport, and architectural marvels like One World Trade Center.

The area has transformed in recent decades, evolving from a primarily business-focused neighborhood to a vibrant mixed-use district. With waterfront access, cobblestone streets in areas like Stone Street, and proximity to Brooklyn via the iconic Brooklyn Bridge, Downtown Manhattan offers visitors a blend of American history, modern architecture, and diverse dining options.

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